WEEK 4 NFL PICKS FOR BET REGAL

Denver at Las Vegas (-2.5)

The Raiders are too talented to be stay winless after winning 10 games last season. Russell Wilson still hasn’t found a rhythm in Denver’s offense and rookie coach Nathaniel Hackett has made several head-scratching decisions. It’s an opportunity for Raiders coach Josh McDaniels to get his first win since Nov. 14, 2010, when he coached the Broncos.

BEST BET: RAIDERS 24-19

Arizona at Carolina (-1)

The Cardinals have struggled in the first half and need to start games the way they finish them. They’ve won nine straight road games in the regular season. Kyler Murray should outduel Baker Mayfield in the battle between former Oklahoma quarterbacks.

UPSET SPECIAL: CARDINALS 26-20

Los Angeles Chargers (-6) at Houston

Justin Herbert is playing hurt, the Chargers are banged-up and they were blown out by the Jaguars last week. The winless Texans have been outscored a combined 30-0 in the fourth quarter this season.

CHARGERS 30-16

Jacksonville at Philadelphia (-6.5)

Jalen Hurts and the Eagles are rolling. They dominated Carson Wentz last week and have another reunion against coach Doug Pederson, who led them to the franchise’s only Super Bowl title.

EAGLES 27-17

Los Angeles Rams at San Francisco (-1.5)

The 49ers have owned the Rams the past three years, winning six straight, though Los Angeles beat San Francisco in the NFC championship game.

49ERS 23-20

Minnesota (-3.5) at New Orleans 

The Saints, especially Jameis Winston, need to stop turning the ball over. The Vikings are still finding their offensive groove under new coach Kevin O’Connell.

SAINTS 23-20

Tennessee at Indianapolis (-3.5)

Matt Ryan rallied the Colts to their first win of the season in a comeback victory over the Chiefs. Now, he gets his first taste of this AFC South rivalry.

COLTS 24-21

Chicago at New York Giants (-2.5)

The Bears have won two games without testing Justin Fields too much. He’s thrown only 45 passes. The Giants have a short week after a tough loss at home to Dallas on Monday night.

GIANTS 22-16

Jets at Pittsburgh (-3.5)

The Steelers are sputtering offensively under Mitch Trubisky. The Jets have held a lead for just 22 seconds.

STEELERS 21-17

Cleveland (-1.5) at Atlanta 

Jacoby Brissett is proving he’s more than a game-manager for the Browns, who rely on Nick Chubb and an excellent ground game.

BROWNS 27-19

Washington at Dallas (-3)

Cooper Rush is 2-0 filling in for Dak Prescott this season. Carson Wentz tries to bounce back from a beatdown against the Eagles to face another familiar opponent.

COWBOYS 23-21

New England at Green Bay (-9.5)

After beating Tom Brady and the Buccaneers, the Packers face the reeling Patriots.

PACKERS 30-13

Buffalo (-3) at Baltimore 

Josh Allen and the Bills ran out of time last week in an exhausting game in Miami. Lamar Jackson is off to an MVP-caliber start.

BILLS 27-26

Seattle at Detroit (-3.5)

The Lions are better than their 1-2 record. The Seahawks are exactly where they should be.

LIONS 30-17

Kansas City at Tampa Bay (-1)

The Buccaneers are in hurricane upheaval, struggling on offense and facing a team seeking to get even for its loss in the Super Bowl two years ago.

CHIEFS 24-21

2022 RECORD

Last Week: Straight up: 10-6. Against spread: 10-6.

Season: Straight up: 27-21. Against spread: 24-24.

Best Bet: Straight up: 1-0. Against spread: 1-0.

Season: Straight up: 2-1. Against spread: 2-1.

Upset Special: Straight up: 1-0. Against spread: 1-0.

Season: Straight up: 1-2. Against spread: 1-2

(Associated Press)